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KMID : 0358819820090010031
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Journal of Korean Society of Plastic and Reconstructive Surgeons
1982 Volume.9 No. 1 p.31 ~ p.37
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EFFECT OF COLD WATER THERAPY ON THE BURNED TISSUE IN RATS
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마흥수/Ma, H.S.
주상용/함기선/박경희/안용팔/Joo, S.Y./Ham, K.S./Park, K.H./Ahn, Y.P.
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Abstract
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Lewis( 1930) & Langohr (1949) suggested that cold water therapy (CWT) reduces tissue metabolism, oxygen debt and dilates minute vessels, therefore increasing blood flow, on the burned tissue in rats. So this method diminishes tissue damage due to impaired circulation and may retard the development of infection.
These experiments were performed to study the effects of CWTon the burned tissue in rats .
Full thickness scald burns (´80c, losec) were inflicted on the backs of the 42 rats .
Burned rats were divided into 2 groups : 27 rate as an experimental group (immediate and delayed CWT) and 15 rats as an untreated control . The untreated control was sacrificed on the 1/ 2 th, Ist , 8 th, 24 tit and 72 th hour after burn.
Immediate CWTgroup was immersed immediately into the cold water (1-2°c, 10min) after burn and sacrificed as same as the time of untreated control. Delayed CWr group was burned and CW)` was performed after 5 min, 10 min, 20min and 30 min delay. They were sacrificed on the 24th hour after burn.
The specimens taken from all experimental animals were fixed in 10 % neutral formaliri, embedded in paraffin wax, sectioned at a thickness of 5 um, and stained with hematoxylineosin for general histologic findings. Observation was made of morphological changes in the collagen fibers, capillaries and separations between collagen fibers located in the skin of rats.
The results were as follows
1. The tissue injury of immediate CWTgroup was less severe than untreated control . 2. The more CWT is delayed; the more tissue injury is aggravated. So immediate CWT is the most effective modality in the CWT of burned tissue.
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